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The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States
PROMOGRAN®
PROMOGRAN® is sterile, freeze-dried composite of 55% collagen and 45% oxidised regenerated cellulose (ORC).
PROMOGRAN® is designed to promote an optimal healing environment 1
With PROMOGRAN® stalled wounds close:
• Faster 1,2
• Cost Effectively 1,3,4
In the presence of exudate the PROMOGRAN® protease modulating matrix transforms into a soft and conformable, biodegradable gel: this allows contact with all areas of the wound.
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The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States
© Systagenix Wound Management 2011. Brands marked with ® or ™ are trademarks of Systagenix. All other products referenced herein are acknowledged to be trademarks of their respective owners.
Disclaimer
The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States
How PROMOGRAN® Works
Collagen/ORC has been proven to reduce levels of proteases such as MMPs and Elastase.
This may restore the balance of the wound microenvironment, promoting granulation tissue and helping the wound close.5

By reducing both MMP and Elastase activity the wound surface area has been shown to reduce. Collagen alone has been shown to be less effective at reducing protease activity.

Click here for further information on the role of Proteases in wound healing.
Disclaimer
The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States
Disclaimer
The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States
PROMOGRAN® Evidence
Please click on the table below for the full list of PROMOGRAN® evidence:
For more detailed clinical and in vitro work on the benefits of PROMOGRAN®, please click one of the links below.
- OWM Health Economic Supplement, November 2010
- Wounds International MMPs Made Easy
- Wounds International PROMOGRAN® & PROMOGRAN PRISMA® Made Easy
- Cullen at al EWMA 2010 ORC
- Cullen et al EWMA 2010 evidence
- Cullen et al (2009) SAWC Poster (In-vitro, Clinical)
- SAWC 2009 Bacteria BC.
- SAWC poster Promogran+awd cell CWF
- Silcock (2009) SAWC Poster (Review)
- Reed Promogran plus VAC (Case Study)
- DFU poster WUWHS July 04.pdf
- Evidence Poster Harrogate 2010. CollagenORC
Click here for further information on the role of Proteases in wound healing.
View the new OWM Educational website on Proteases in Wound Care
Systagenix is not responsible for the content of external websites.
Disclaimer
The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States
PROMOGRAN® Indications
PROMOGRAN® matrix is indicated for the management of all wounds
healing by secondary intent which are clear of necrotic tissue, including:
- Diabetic ulcers
- Venous ulcers
- Pressure ulcers
- Ulcers caused by mixed vascular aetiologies
- Traumatic and surgical wounds
PROMOGRAN® matrix has demonstrated haemostatic properties.
PROMOGRAN® matrix can be used under compression therapy.
Please refer in full to the Instructions for use leaflet provided in the product packaging, specific to your region.















