WOUNDCHEK™ Protease Status
Why test for EPA?
Chronic wounds with elevated protease activity (EPA)
have a 90% probability they won’t heal1 (without appropriate intervention)
But
only 28% of non-healing wounds have EPA1
And
there are no visual cues to detect EPA2,3
Non-healing wounds cost billions to the healthcare system4,5
So, how do you know which wounds have EPA?
Developed to aid wound assessment and help clinicians target advanced wound care therapies more effectively, WOUNDCHEK™ Protease Status is able to detect EPA. As there are no clinical signs for EPA, wounds with EPA have so far gone undetected2,3. WOUNDCHEK™ Protease Status will help clinicians establish within minutes which wounds may most benefit from a protease modulating therapy, ensuring appropriate and targeted use of these therapies.
Please refer in full to the Instructions for use leaflet provided in the product packaging, specific to your region.
The image shown depicts a test result for a wound with EPA
Systagenix is not responsible for the content of external websites.
Disclaimer
The product information on this page is not intended for, or to be used by health care professionals or users in the United States
WOUNDCHEK™ Protease Status
- Rapid point of care test
- Easy to use
- Detect EPA in 15 minutes
- Know which wounds to treat with protease modulating therapy
View demonstration videos
Click here to view our online demo of how to obtain a sample and how to perform the test
Please refer in full to the Instructions for use leaflet provided in the product packaging, specific to your region.6
Systagenix is not responsible for the content of external websites.
Disclaimer
The product information on this page is not intended for, or to be used by health care professionals or users in the United States
WOUNDCHEK™ Protease Status
For more information on the potential clinical value of a protease test, click one of the links below:
Defining EPA (elevated protease activity) and why a test able to detect EPA is needed and clinically relevant:
- Protease Activity Levels Associated with Healing Status of Chronic Wounds
- The Importance of Proteases in Wound Healing and Wound Assessment
- The role of Proteases in Wound Diagnostics consensus
- You Can’t Manage What You Can’t Measure: Welcome to 21st Century Wound Care
Diagnostics in wound care:
Understanding proteases and healing in wound care:
- What's the Delay? The Role of Inflammatory Proteases in Wound Healing
- MMPs Made Easy
- Do you know your Proteases?
- Webcasts of Cape Town Symposium
- Systagenix sponsors virtual conference with Wounds International
- Visit the proteasemarker website
Please refer in full to the Instructions for use leaflet provided in the product packaging, specific to your region.
The image on the right shows a wound with EPA
Systagenix is not responsible for the content of external websites.
Disclaimer
The product information on this page is not intended for, or to be used by health care professionals or users in the United States
WOUNDCHEK™ Protease Status
WOUNDCHEK™ Protease Status is an in vitro, visually read, immunochromatographic test for the qualitative assessment of human neutrophil-derived inflammatory protease activity directly from wound fluid swab samples taken from chronic wounds.
Definition of a chronic wound:
A chronic wound is a wound that fails to progress through a normal, orderly, timely sequence of repair and where co morbidities interfere with the normal healing process7. This encompasses wounds described as delayed, stalled, hard to heal, recalcitrant, difficult, complex, or failing to respond and could include acute wounds that have healing problems. Chronicity is not necessarily dependent on the time since the wound was first formed8.
Please refer in full to the Instructions for use leaflet provided in the product packaging, specific to your region6.
The image on the right shows a wound with EPA
Systagenix is not responsible for the content of external websites.
Disclaimer:
The product information on this page is not intended for, or to be used by health care professionals or users in the United States














