Let’s Heal™ is the result of 75 years experience in developing our products to help you test, protect, promote and comfort the wound towards healing.

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Evidence

 

Evidence
type
Type Year of
publication
Author Title
Level one - RCT study Evidence summary 2007 Lázaro-Martinez, J.L. Randomized comparative trial of a collagen/oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers
Level one - RCT study Evidence summary 2005 Nisi, G. Use of a protease modulating matrix in the treatment of pressure sores
Level one - RCT study Evidence summary 2005 Wollina, U.,
et al.
Some effects of a topical collagen-based matrix on the microcirculation and wound healing in patients with chronic venous leg ulcers: preliminary observations.
Level one - RCT study Evidence summary 2002 Veves, A.,
et al.
A randomized controlled trial of PROMOGRAN®  vs standard treatment in the management of diabetic foot ulcers
Level one - RCT study Evidence summary 2002 Vin, F.,
et al.
The healing properties of PROMOGRAN®; in venous leg ulcers
Clinical Poster 2012 Cullen, B.,
et al.
Early adoption of collagen/ORC therapies improves clinical outcome
Clinical Article 2010 Harding, K.,
et al.
Health Economics: utilizing advanced care wound products for clinical and cost effectiveness
Clinical Poster 2004 Thomas, R.,
et al.
Audit of costs and outcomes of PROMOGRAN® usage within a cohort of patients with diabetic foot ulcers
Clinical / in vitro Poster 2009 Cullen, B.,
et al.
The effect of collagen-based wound dressings on bacterial growth
Clinical / in vitro / ex vivo Poster 2011 Cullen, B.,
Silcock, D.
Evidence for collagen/ORC therapies - in vitro, ex vivo and in clinical practice
Clinical / in vitro / in vivo Poster 2009 Silcock, D. Evidence for wound therapies - in vitro, in vivo, in practice
In vitro Poster 2010 Cullen, B.,
et al.
Use of oxidized regenerated cellulose in facilitating wound healing
In vitro Poster 2007 Cullen, B.,
et al.
Modulation of the chronic wound environment; an in vitro evaluation of advanced wound therapies
In vitro / ex vivo Poster 2010 Cullen, B.,
Silcock, D.
Collagen/Oxidized regenerated cellulose therapies in managing chronic wounds
Case study Article 2013   Using PROMOGRAN®/PROMOGRAN® PRISMA in wounds with elevated protease activity: case studies
Case study Poster   Reed, D. Combination therapy for full thickness wounds utilizing an ORC/collagen matrix dressing and negative pressure therapy
Product review Article 2010 Cullen, B.,
Ivins, S.
PROMOGRAN® & PROMOGRAN® PRISMA made easy
  Article 2009 Gibson, D.,
et al.
MMPs made easy

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Further information:
The role of Proteases in wound healing
OWM Educational website on Proteases in Wound Care

 
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Disclaimer
The product information on this page is not intended to be used by health care professionals or users in the United States and may not comply with the regulatory standards of the United States – please click the link above for product information in respect of products used in the United States

References

References


1. Lazaro-Martinez et al. Randomized comparative trial of a collagen/oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers. F.R. Circ. Esp.2007, 82(1), 27-31


2. Veves A et al. A randomized , controlled trial of Collagen/ORC vs standard treatments in the management of diabetic foot ulcers. Arch Surg 2002;137:822-827

3. Snyder. Sequential therapies and advanced wound care products as a standard practice in the home care setting. Home health abstract for SAWC, San Diego, April 2008 (presentation at the J&J satellite symposium)

4. Ghatenekar O. Willis. M. Persson U. Health Economics. ‘Cost effectiveness of treating deep diabetic foot ulcers with collagen/ORC in four European countries’. J Wound Care, Vol 11, No2. Feb 2002

5. Cullen B, Smith R, McCulloch E, Silcock D, Morrison L. Mechanism of action of Collagen/ORC, a protease modulating matrix for treatment of diabetic foot ulcers. Wound Rep Regen 2002;10:16-25.

11. Cullen, B., Kemp, L., Essler, L. Rebalancing wound biochemistry improves healing: a clinical study examining effect of PROMOGRAN. Wound Repair Regen. 2004 12(2) A4

12. Cullen et al. A comparison of collagen containing dressings to modify the chronic wound environment. EWMA 2007

13. Cullen, B., Boyle, C., Webb, Y. Modulation of the chronic wound environment; an in vitro evaluation of advanced wound therapies. SAWC, Tampa FL, 2007.