WOUNDCHEK™ Protease Status
- Chronic wounds with EPA (elevated protease activity) have a 90%
probability they won’t heal1 (without appropriate intervention).
- 28% of non-healing wounds have EPA1there are no visual cues to detect EPA2,3
- Non-healing wounds cost billions to the healthcare system4,5
So, how do you know which wounds have EPA?
Developed to aid wound assessment and help clinicians target advanced wound care therapies more effectively, WOUNDCHEK™ Protease Status is able to detect EPA. As there are no visual cues for EPA, wounds with EPA have so far gone undetected2,3. WOUNDCHEK™ Protease Status will help clinicians establish within minutes which wounds may most benefit from a protease modulating therapy, ensuring appropriate and targeted use of these therapies.
Please refer in full to the Instructions for use leaflet provided in the product packaging, specific to your region.
Evaluation of the use of a point of care test for proteases to identify patients with increased risk of skin graft failure
Video: Why test for EPA (elevated protease activity)
NHS recommends assessment for elevated protease activity using diagnostic test to help decide venous leg ulcers treatment pathway
Tissue viability service at Brentwood community hospital is first to purchase new test for wounds
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The product information on this page is not intended for, or to be used by health care professionals or users in the United States
WOUNDCHEK™ Protease Status references
1. Serena T. et al. Protease activity levels associated with healing status of chronic wounds.Poster, Wounds UK 2011.
2. Snyder R. et al. A survey: The importance of proteases in wound healing and wound assessment. Poster, Wounds UK 2011.
3. International consensus. The role of proteases in wound diagnostics. An expert working group review. London: Wounds International, 2011.
4. Gordois A, Scuffham P, Shearer A, Oglesby A, Tobian JA. The healthcare costs of diabetic peripheral neuropathy in the US. Diabetes Care. 2003;26(6):1790–1795.
5. Shearer A, Scuffham P, Gordois A, Oglesby A. Predicted costs and outcomes from reduced vibration detection in people with diabetes in the U.S. Diabetes Care. 2003;26(8):2305–2310.
6. Instructions for Use 2011.
7. Lazarus GS, Cooper DM, Knighton DR, et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Arch Dermatol. 1994;130(4):489-493.
8. Consensus on Use of a Diagnostic Tool in Stalled Wounds to Identify Excess Protease Levels. The Protease Diagnostic Consensus Panel. Ostomy Wound Management. Ostomy Wound Management 2011;57(12): 36-48.